Triple Helix Science Evidence Atlas

Illustrative healthspan model

Framing inputs

These are used only to frame the illustration. Nothing is stored, and nothing is transmitted anywhere — the model runs entirely in your browser.

45
1885
Biological sex

How this is calculated (read this)

Step 1 — a range per intervention

Each intervention carries a range of plausible added healthspan years, weighted by the strength of its evidence and its plausible potential. Gene-therapy entries reflect preclinical potential in animals, not human evidence — read those ranges as what the biology might allow, not what has been shown in people.

Step 2 — fundamentals carry more weight

Five fundamentals sit above the rest because their human evidence is unusually deep: cardiorespiratory fitness, resistance training, the Mediterranean pattern, sleep optimization and caloric restriction.

Step 3 — diminishing returns by rank

Selected interventions are sorted strongest first, then each successive one counts for less: the strongest counts in full, the next at 80%, the next at 64%, and so on (0.80 per rank). Stacked interventions share biological mechanisms, so they never simply add up — but adding one can never lower the total either.

Step 4 — the illustrative window

Age and sex set a teaching baseline for expected age at death, and the added-years range is laid on top of it. A few interventions carry sex-specific evidence and are weighted accordingly. The projected window is capped at 135 years.

What this is not

Not a diagnosis. Not a personalized prognosis. Not a substitute for clinical judgment. It cannot tell you what will happen to you.

The largest honest gains come from the fundamentals — fitness, muscle, sleep, diet and cardiovascular risk control. That is exactly why they carry the heaviest bars here, and why the exotic entries carry thin ones.

Select interventions

73 entries

GEN — Genomics

SEN — Senescence

MET — Metabolic

NAD — NAD+ pathway

EPI — Epigenetics

LIF — Lifestyle

STM — Stem cells

INF — Inflammation

MIC — Microbiome

HRM — Hormonal